Only linear agents are retained in our patient?

The correct answer is that it is false that only linear agents are retained in patients. Both linear and macrocyclic gadolinium-based contrast agents (GBCA) can be used in MRI. However, the retention of these agents in the body can vary based on multiple factors, such as the specific type of agent being used, the dosage, the patient's renal function, and the frequency of administration.

Macrocyclic agents, for example, are known to have a lower risk of retention and accumulation in tissues compared to linear agents due to their more stable structure. This stability makes macrocyclic agents less likely to release gadolinium into the body. Conversely, linear agents are associated with a greater risk of gadolinium retention, especially in patients with compromised renal function, which can lead to conditions like nephrogenic systemic fibrosis (NSF).

Patient conditions, such as the presence of chronic kidney disease or other factors impacting renal clearance, play a significant role in determining how long contrast agents remain in a patient's system. Thus, the statement that only linear agents are retained oversimplifies and does not accurately reflect the complexities involved in contrast agent retention.