What is the primary purpose of testing eGFR prior to administering gadolinium-based contrast agents?

The primary purpose of testing estimated Glomerular Filtration Rate (eGFR) prior to administering gadolinium-based contrast agents is to assess renal function. This evaluation is crucial because gadolinium-based contrast agents can pose a risk of nephrogenic systemic fibrosis (NSF) in patients with impaired kidney function. By measuring eGFR, healthcare providers can determine whether a patient's kidneys are functioning adequately to safely eliminate the contrast agent from the body following its use in imaging procedures like MRI. If renal function is compromised, the use of gadolinium-based contrast may be contraindicated or require careful consideration and alternative approaches.

Understanding a patient’s renal function through eGFR testing helps ensure that the benefits of using the contrast agent outweigh any potential risks, particularly concerning kidney health.